Saturday, January 7, 2012

Genetically modified monkeys born in US

The world's first genetically modified monkeys have been created in the US, with researchers fusing cells from up to six different embryos.

Until now, rodents have been the primary creatures used to make chimeras, a lab animal produced by combining two or more fertilised eggs or early embryos together.

Scientists have long been able to create "knockout" mice with certain genes deleted in order to study a host of ailments and remedies, including obesity, heart disease, anxiety, diabetes and Parkinson's disease.

Attempts to do the same with more complicated primates have failed in the past, but scientists in the western US state of Oregon succeeded by altering the method used to make mice.

The breakthrough came when they mixed cells together from very early stage rhesus monkey embryos, in a state known as totipotent, when they are able to give rise to a whole animal as well as the placenta and other life-sustaining tissues.

The experiment produced three healthy male rhesus monkeys they named Roku, Hex and Chimero, with gene traits from all of the separate embryos used to meld them.

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